The A-list pair, who were rumoured to be tying the knot this weekend, confirmed that they are now husband and wife in a statement to a US magazine.
The newlyweds said: "It's great to be married, the ceremony was beautiful and it was so special to be surrounded by our family and friends."
Hollywood's gorgeous couple, who got engaged last December, are believed to have tied the knot in a secluded location in Southern Italy.
According to our sister site in the US, their vows were exchanged at Francis Ford Coppola's Palazzo Margherita in Bernalda, a small hilltop town near the Ionian Sea.
Justin, 31, and Jessica, 30, who have been together five years, had kept pretty quiet about their nuptials in the run up to the big day, keeping the location, guests and details top secret.
But this week they were spotted with guests enjoying pre-wedding drinks at a spot in Southern Italy.
On Wednesday they reportedly hosted a beach party in Puglia, which featured jazz music and a 10-minute fireworks display.
The following day guests apparently gathered at a grotto in Lama del Trappeto where they relaxed and ate wine and cheese.
[Related story: Justin and Jessica throw pre-wedding bash]
According to The Sun, Justin was going to surprise his wife by performing a comedy dance routine to allude to his 'N Sync days.
Congrats to the gorgeous pair. Hands up who reckons they will have beautiful children.